Folate deficiencies studied in 38 old persons (62 + 5 years) are accompanied by neuropsychiatric disturbances such as depression, asthenia, irritability, forgetfulness and lack of attention. These symptoms disappear with a treatment by folinic acid.
High dose folate significantly improved:9
- visual-spatial memory 3
- perception and visual-spatial
- organization 5
- associative memory 10
- logical reasoning 12
- maze delay 13