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Folate Deficiency and Elderly Memory Loss




1.   Vitamin B12-B6-Folate treatment improves Blood-Brain Barrier function in patients with Hyperhomocysteinaemia and Mild Cognitive Impairment
Lehmann M, Regland B, Blennow K, and Gottfries CG.
Dementia and Geriatric Cognitive Disorders 2003;16:145-150.



2.   Improvement of cognitive functions after cobalamin/folate supplementation in elderly patients with dementia and elevated plasma homocysteine.
Nilsson K, Gustafson L, and Hultberg B.
International Journal of Geriatric Psychiatry. 2001;16:609-614.



3.   Pathogenicity of Thermolabile Methylenetetrahydrofolate Reductase for Vascular Dementia
Jun-Hyun Yoo; Gyu-Dong Choi; Soo-Sang Kang
Arterioscler Thromb Vasc Biol. 2000; 20:1921-1925



4.   Short-Term Folate, Vitamin B-12 or Vitamin B-6 Supplementation Slightly Affects Memory Performance But Not Mood in Women of Various Ages.
Bryan J, Calvaresi E and Hughes D.
J. Nutr. 2002;132:1345-1356.



5.   Folate deficiency in elderly subjects: value of folate supplementation in the management of behavior disorders. (In French)
Brocker P, Lebel C, Maurin H, Lods JC.
Sem Hôp Paris. 1986;62(27):2135-2139.



6.   Reduced risk of Alzheimer's disease with high folate intake: The Baltimore Longitudinal Study of Aging.
Corrada M, Kawas C, Halldrisch J, Muller D, Brookmeyer R.
Alzheimer's & Dementia. 2005;1:11-18.



7.   Effects of 3-year Folic Acid Supplementation on Cognitive Function in Older Adults in the FACIT trial: A randomized, double-blind, controlled trial.
Durga J, van Boxtel PJ, Schouten EG, Kok FJ, Jolles J, Katan MB, Verhoef P.
The Lancet. 2007;369:208-215.



8.   Low folate levels in the cognitive decline of elderly patients and the efficacy of folate as a treatment for improving memory deficits.
Fioravanti M, Ferrario E, Massaia M, Cappa G, Rivolta G, Grossi E and Buckley AE.
Arch Gerontol Geriatr. 1997;26:1-13.



9.   Vitamin B12-B6-Folate treatment improves Blood-Brain Barrier function in patients with Hyperhomocysteinaemia and Mild Cognitive Impairment
Lehmann M, Regland B, Blennow K, and Gottfries CG.
Dementia and Geriatric Cognitive Disorders 2003;16:145-150.



10.   Folate and vitamin B-12 status in relation to anemia, macrocytosis, and cognitive impairment in older Americans in the age of folic acid fortification.
Morris MS, Jacques PF, Rosenberg IH, Selhub J.
Am J Clin Nutr. 2007;85:193-200.



11.   Blood Folates Deficiencies and Cognitive Functions in Aging.
Rapin JR, Le Poncin M, Grebyl J.
In Steinhagen-Thiessen E and Knook DL, ed. Trends in Biomedical Gerontology. Vol. 1. Rijswijk, The Netherlands: TNO Institute for Experimental Gerontology; 1987:221-223.